A Steady State of Morphogen Gradients for Semilinear Elliptic Systems

Existence and multiplicity of positive solutions for a class of semilinear elliptic system with nonlinear boundary conditions

This study concerns the existence and multiplicity of positive weak solutions for a class of semilinear elliptic systems with nonlinear boundary conditions. Our results is depending on the local minimization method on the Nehari manifold and some variational techniques. Also, by using Mountain Pass Lemma, we establish the existence of at least one solution with positive energy.

When it pays to rush: interpreting morphogen gradients prior to steady-state.

During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest that some morphogen gradients may be interpreted prior to reaching steady-state. Theoretical work has predicted that such systems will be more robust to embryo-to-embryo fluctuations. By analyzing two experimentally mo...

Robustness of Morphogen Gradients with "bucket Brigade" Transport through Membrane-associated Non-receptors.

Robust multiple-fate morphogen gradients are essential for embryo development. Here, we analyze mathematically a model of morphogen gradient (such as Dpp in Drosophila wing imaginal disc) formation in the presence of non-receptors with both diffusion of free morphogens and the movement of morphogens bound to non-receptors. Under the assumption of rapid degradation of unbound morphogen, we intro...

The Nehari Manifold for a Class of Indefinite Weight Semilinear Elliptic Equations

EXISTENCE OF A STEADY FLOW WITH A BOUNDED VORTEX IN AN UNBOUNDED DOMAIN

We prove the existence of steady 2-dimensional flows, containing a bounded vortex, and approaching a uniform flow at infinity. The data prescribed is the rearrangement class of the vorticity field. The corresponding stream function satisfies a semilinear elliptic partial differential equation. The result is proved by maximizing the kinetic energy over all flows whose vorticity fields are rearra...